Yes. The backup software will back up files of any type, including SQL data files (and SQL log files and SQL backup files as well).
SQL files can often be very large in size, so be sure to verify that your SQL database files meet the maximum file size requirements of your plan.
Lastly, while you can use the backup software to backup open and active SQL files, our recommendation is that you utilize the "native" backup tools (the tools built right into SQL) to produce a point-in-time backup file or a ".bak" file. Then use our software to backup the file directory where you have the ".bak" file stored.
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